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How Uterine Fibroids Affect Perimenopausal Women

How to Prepare for a Myomectomy: A Step-by-Step Guide
Dr Anthony Siow
Dr Anthony Siow
Medical Director & Consultant Obstetrician & Gynaecologist
MBBS, M Med (O&G),
FRCOG (UK), MRANZCOG (Aust-NZ)
MRCOG (RCOG, UK), FAMS (S'pore)
Member of the Australasian Gynaecological Endoscopy and Surgery Society
Member of the American Association of Gynecologic Laparoscopists

Perimenopause usually begins in a woman’s 40s, although some may notice changes as early as their mid-30s. This stage marks the transition leading up to menopause, when hormone levels fluctuate and menstrual cycles may become irregular.

For women with uterine fibroids, these hormonal shifts can sometimes worsen fibroid symptoms or overlap with perimenopausal changes. With proper awareness and medical guidance, many women can manage these changes more comfortably.

Why Fibroids May Change During Perimenopause

During perimenopause, hormonal fluctuations can influence how uterine fibroids behave. Some fibroids remain stable, while others may grow or cause more noticeable symptoms. Several factors may contribute to these changes:

Hormonal Fluctuations and Oestrogen Levels

Oestrogen and progesterone levels fluctuate significantly in the years leading up to menopause rather than declining steadily. These hormonal changes can stimulate fibroid growth or make existing fibroids more symptomatic, particularly when oestrogen levels remain relatively high.

Hormonal Medications

Some women use hormonal treatments, such as birth control pills or hormone replacement therapy (HRT), to manage perimenopause-related symptoms. In certain cases, additional oestrogen exposure may contribute to fibroid growth or make symptoms more noticeable.

Genetic Factors and Family History

Genetics can also influence fibroid development. Women with a family history of fibroids may develop them earlier and may continue to experience symptoms during perimenopause as hormonal changes interact with inherited risk factors.

How Uterine Fibroids Can Affect Women During Perimenopause

Perimenopause already brings hormonal changes that can affect both the body and mood. When uterine fibroids are also present, these symptoms may become more noticeable and can influence daily comfort, emotional well-being and overall quality of life.

Emotional Fatigue

Repeated cycles of heavy bleeding, pelvic pain and disrupted sleep can gradually drain physical and emotional energy. Over time, coping with these symptoms month after month may leave some women feeling exhausted or overwhelmed.

Increased Mood Changes

Hormonal fluctuations during perimenopause can already influence mood. When fibroids contribute to pain or heavy bleeding, they may further intensify irritability, anxiety or emotional shifts.

Disruptions to Daily Life

Symptoms such as unpredictable bleeding, pelvic pressure or urinary frequency may interfere with work, travel or social activities. These disruptions can make it harder to maintain normal routines.

Mental Burden

Many women feel uncertain about whether their symptoms relate to perimenopause, fibroids or another condition. This uncertainty can delay seeking medical care and add unnecessary stress.

Changes in Body Confidence

Symptoms such as bloating, abdominal heaviness or ongoing discomfort may affect how women feel in their own bodies. When these changes continue over time, they may influence self-confidence and overall well-being.

How Can Fibroids During Perimenopause Be Treated?

If you have uterine fibroids during perimenopause, your doctor will discuss several treatment options based on your symptoms, fibroid size and personal health goals. Many women do not require immediate surgery and treatment can range from monitoring to more active interventions. Common management options include:

  • Expectant Management (Monitoring): Doctors may recommend regular monitoring if the fibroids are small and symptoms are mild.
  • Medical Therapies: Medications may help manage symptoms such as heavy bleeding or pelvic discomfort.
  • Minimally Invasive Treatments: Certain procedures can reduce fibroid size or relieve symptoms while limiting recovery time.
  • Surgical Interventions: In some cases, doctors may recommend surgery to remove fibroids or address severe symptoms.

Your doctor may perform tests to determine the most suitable treatment approach. These tests may include a pelvic ultrasound, which evaluates the size and location of fibroids and blood tests, which assess hormone levels that may influence fibroid growth.

When Should Perimenopausal Women See a Doctor for Fibroids?

Although fibroids are common during perimenopause, certain symptoms should prompt medical evaluation. You should consider seeing a doctor if you experience unusually heavy or prolonged menstrual bleeding, persistent pelvic pain or increasing abdominal pressure.

Medical advice is also recommended if symptoms begin to interfere with daily activities, cause fatigue or worsen over time. Early assessment allows your doctor to determine whether fibroids are contributing to these changes and to recommend appropriate monitoring or treatment.

A doctor and an illustration of the female reproductive system

Maintaining Reproductive Health During Perimenopause

Uterine fibroids can interact with the hormonal changes of perimenopause in ways that make symptoms more noticeable or difficult to interpret. Understanding these changes can help women recognise when symptoms may require medical attention. With appropriate evaluation and guidance from a doctor, many women can manage fibroids and perimenopausal changes more effectively.

At our fibroid clinic, we take a patient-centred approach to fibroid care, offering evidence-based treatment plans tailored to each woman’s symptoms, health needs and preferences. Care is led by Dr Anthony Siow, who has more than two decades of experience in fibroid management and laparoscopic surgery. If you are experiencing persistent symptoms or concerns about fibroids during perimenopause, arrange a consultation for a detailed evaluation and personalised care.

FAQs About How Uterine Fibroids Affect Perimenopausal Women

Meet Our Specialist

Dr Anthony Siow

Obstetrician Gynaecologist

MBBS, M Med (O&G), MRANZCOG, MRCOG

Member of the Australasian Gynaecological Endoscopy and Surgery Society

Member of the American Association of Gynecologic Laparoscopists

Dr Anthony Siow has more than 20 years of experience in obstetrics and gynaecology. He previously served as Director of Minimally Invasive Surgery at a public hospital in Singapore and helped develop programmes for managing complex gynaecological conditions, including fibroids, ovarian cysts and endometriosis.

He was also the first gynaecologist in Singapore to perform single-incision laparoscopy for procedures such as hysterectomy and myomectomy, providing an additional minimally invasive option for women who require fibroid surgery. Dr Siow focuses on careful evaluation and evidence-based treatment to help women manage gynaecological conditions safely and effectively.

Dr Anthony Siow
Fibroid Singapore
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